Most injectables make a choice: volume now, or collagen later. HArmonyCa, Allergan‘s first-ever hybrid injectable, refuses to choose. It delivers both: immediate lift from hyaluronic acid and sustained collagen rebuilding from calcium hydroxyapatite, in a single syringe. Lucere Dermatology & Laser Clinic is among the first clinics in Canada to offer HArmonyCa, and if you’ve been curious about what all the buzz is about, here’s everything you need to know.
A New Category of Injectable, Not Just Another Filler
The injectable market has spent decades in one of two lanes: dermal fillers that add volume, and biostimulators that trigger the body’s own collagen. Great options exist in both categories. But they work differently, they’re administered differently, and until now, getting the benefits of both meant two separate treatments.
HArmonyCa changes that. Developed by Allergan—the same company behind Botox and Juvéderm—it is the world’s first injectable to combine cross-linked hyaluronic acid (HA) and calcium hydroxyapatite (CaHA) microspheres in a single, ready-to-use syringe. The result is a treatment that acts immediately and keeps working long after you’ve left the clinic.
This is not a minor product update. It’s a genuinely new category and it has earned significant attention from aesthetic medicine specialists worldwide since its launch.
How HArmonyCa Works: The Dual-Action Mechanism
Step 1: Immediate Lift from Hyaluronic Acid (HA)
The moment HArmonyCa is injected, the cross-linked HA gel integrates into the deep dermal and subdermal layers, restoring lost volume and lifting tissues that have gradually descended with age. You walk out of the treatment looking refreshed. Not different. Refreshed.
The HA in HArmonyCa is cross-linked for longevity, meaning it resists breakdown and maintains its volumizing effect while the second mechanism begins its work.
Step 2: Collagen Rebuilding from Calcium Hydroxyapatite
Over the weeks and months following treatment, the CaHA microspheres in HArmonyCa act as a biostimulator. They deposit a structural scaffold within the dermis, signalling fibroblast cells — your skin’s collagen factories — to begin producing new collagen fibres. This process typically begins within one week of treatment and continues building over one to two months, delivering progressive improvements in skin firmness, density, and elasticity.
The net effect: results that get better over time. The immediate lift you see on day one evolves into a broader structural improvement in skin quality: tighter, firmer, and more naturally youthful in character.
What Makes HArmonyCa Different from Standard Fillers?
Standard HA filler: Adds volume immediately. Gradually broken down by the body over six to twelve months. Results are reversible. No collagen stimulation.
Sculptra (biostimulator): Stimulates collagen over time. No immediate results. Requires multiple sessions.
Radiesse (CaHA filler): Volume + some collagen stimulation, but without the combined HA volumizing component.
HArmonyCa: Immediate lift from HA + long-term collagen stimulation from CaHA. Both effects. One treatment. Results lasting 12–18 months, with potential for longer duration with a follow-up session.
For patients who want the instant gratification of a filler and the lasting structural benefit of a biostimulator, HArmonyCa represents a meaningful step forward.
Treatment Areas: Where HArmonyCa Works
HArmonyCa is specifically designed for the mid and lower face, the zones where gravitational change is most pronounced and most impactful to overall facial harmony. According to Allergan’s clinical guidelines, primary injection areas include:
- Cheeks and mid-face — restoring volume loss and lifting descended tissues
- Jawline and chin border — improving definition and contour
- Marionette lines and smile lines — smoothing and reducing depth over time
- Jowl area — lifting and tightening tissues prone to sagging
HArmonyCa is not intended for the lips, perioral area, under the eyes, or glabellar lines. Your injector will assess your anatomy and determine the most appropriate treatment plan during your consultation.
The Anatomy of Beauty (AB Face) Approach
Allergan’s recommended framework for HArmonyCa treatment is guided by the Anatomy of Beauty (AB Face) approach: a system that considers each patient’s unique facial shape, bone structure, subcutaneous volume, and aging pattern to design a balanced, harmonious result. Whether your face is angular, heart-shaped, oval, or round, the AB Face approach tailors the injection map to your specific anatomy, not a template.
At Lucere, this philosophy aligns naturally with how Dr. Zaki Taher has always approached injectables: no two faces are the same, and no treatment plan should be either. With over 5,000 injectable treatments administered per year, the Lucere team brings a depth of anatomical knowledge and injection expertise that ensures HArmonyCa is deployed precisely and purposefully.
Lucere Dermatology & Laser Clinic is among the first clinics in Canada to offer HArmonyCa. Dr. Zaki Taher and the Lucere team are taking consultations now. Book your complimentary consultation at lucereskin.com or call 780-461-1188.
What to Expect: The HArmonyCa Treatment Experience
Duration: A HArmonyCa session is typically 15–30 minutes.
Comfort: Lidocaine is included in the formulation, making the treatment more comfortable than many comparable injectables.
Downtime: Minimal. Some swelling, redness, or tenderness at injection sites is expected and typically resolves within a few days.
Immediate results: Visible lift and volume on the day of treatment.
Progressive results: Continued improvement in firmness and skin quality over four to eight weeks as new collagen forms.
Duration of results: 12–18 months for a single treatment. Results can be extended with a follow-up session at six months.
Who Is an Ideal Candidate for HArmonyCa?
HArmonyCa is an excellent option for adults who:
- Are noticing sagging or softening in the cheeks, jawline, or lower face
- Want results that improve over time, not just immediate volume
- Have previously used standard HA fillers and are ready for a more comprehensive approach
- Are interested in fewer appointments with longer-lasting outcomes
- Want natural-looking rejuvenation, not a dramatically altered appearance
HArmonyCa is not appropriate for patients who are pregnant or breastfeeding, have known allergies to any component of the formula, or have active infection at the planned injection sites. A thorough consultation with Dr. Taher will confirm candidacy and establish the right treatment approach for your goals.
Frequently Asked Questions: HArmonyCa
Is HArmonyCa reversible?
Partially. The HA component of HArmonyCa can be dissolved with hyaluronidase, as with standard HA fillers. The CaHA component, however, is not reversible in the same way. This is why expert assessment and precise injection technique matter enormously with this product, which is why choosing an experienced injector is critical.
Can HArmonyCa be combined with other treatments?
Yes. Clinical data and real-world experience support combining HArmonyCa with neuromodulators (Botox), other dermal fillers, and laser treatments. At Lucere, combination treatment planning is a cornerstone of how Dr. Taher approaches full-face rejuvenation, ensuring each treatment works synergistically rather than in isolation.
How does HArmonyCa compare to Sculptra?
Both involve collagen stimulation. Sculptra (poly-L-lactic acid) provides no immediate results and requires multiple sessions to build effect over time. HArmonyCa delivers immediate volume on day one via HA, while the CaHA provides the ongoing collagen-building benefit. For patients who want both, HArmonyCa accomplishes more in a single visit.
How soon will I see results?
Immediately. The hyaluronic acid provides lift and volume on the day of treatment. The collagen-stimulating effects of the CaHA become visible over four to eight weeks, with continued improvement over several months. Most patients notice the full scope of results by the three-month mark.
HArmonyCa is now available at Lucere Dermatology & Laser Clinic — Edmonton South and Downtown. As one of the first clinics in Canada to offer this treatment, Lucere is positioned at the leading edge of what’s possible in non-surgical facial rejuvenation. Book your complimentary consultation with Dr. Zaki Taher at lucereskin.com or call 780-461-1188.